Babies
with Krabbe disease are found to be the perfect candidates for the
cord blood transfusion.
The Krabbe
disease could be a history within the family of the baby. Under such
circumstances the baby should be diagnosed for the Krabbe disease
and cord blood transfusion done at the appropriate time to avoid fatal
consequences. Before
performing a cord blood transfusion the blood from the donor that
is stored in the blood bank is undergone various tests to find out
any problem or infections in the cord blood. Microbacterial
cultures and mycoplasma cultures are done with the cord blood and
the concentration of the prothrombin fragments is analyzed. Cord
blood transfusion is safe in the babies if proper tests of the blood
are done prior to the cord blood transfusion.Cord blood that is requested
from the blood banks can also be safe mostly because they are tested
even before they are stored in the blood banks. You should
always remember that charges associated with acquiring blood from
the banks are costly.That is why most of the donors store the cord
blood in blood banks for private use by their family alone. Blood
collected from the umbilical cord of the infant can be used with the
same infant when necessary. Enzyme disorders that are fatal like the
Krabbe disease require the cord blood transfusion to make the baby
live a normal life with minimal disturbances. Researches
made with auto transfusion of the cord blood have revealed that there
were no problems with the babies after the cord blood transfusion.
Extensive
researches are done and being done in the University of North Carolina
and the Duke University on cord blood transfusion. Studies done on
the babies were made immediately after the birth of the babies. For the
case of study some were done cord blood transfusion after the disease
symptoms appeared. The procedures that were adopted in the researches
included the destruction of the bone marrow with the help of the chemotherapy.
After
the bone marrow destruction the cord blood transfusion was done on
them. Defects
in bone marrow could also have been done with bone marrow transplantation
but cord blood transfusion is found to be the effective method. The advantage
of cord blood transfusion over the bone marrow replacement are many
and some of them are the deficiencies in enzymes are tackled with
immediately.
Understanding
Cord blood transfusion